Acta Crystallographica Section E (Oct 2008)

6,7,9,10-Tetrahydro-16,22-ethanooxyethano-5,8,11,19-tetraoxa-16,22-diazadibenzo[h,q]cyclooctadecine-17,21-dione: a benzylannelated macrobicyclic diamide

  • Richard W. Taylor,
  • Douglas R. Powell,
  • Yang Lei,
  • Gary L. N. Smith

DOI
https://doi.org/10.1107/S1600536808030067
Journal volume & issue
Vol. 64, no. 10
pp. o2003 – o2003

Abstract

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The macrobicyclic title compound, C24H28N2O7, has two tertiary diamide bridgehead atoms and is composed of a 12-membered ring (N2O2 donor set) and two 18-membered rings (N2O4 donor sets). The solid-state structure shows that each of the amide groups is not coplanar with the adjacent benzene ring and NMR studies indicate that this conformational relationship persists in solution.