Paramedian bilateral lip pits with sinuses (Van der Woude syndrome)

Abstract

Genes the basic units of heredity, contain blue prints for human growth and development. A change or alteration in a single gene on chromosome number causes one Van der Woude syndrome (VWS). Features of VWS include lip pits on the lower lip, cleft palate alone or with cleft lip in some cases, missing teeth, syngnathia and ankyloglossia. The features of VWS are discussed along with two clinical case presentations. Bilateral lip pits with sinuses, surgically corrected cleft lip, cleft palate and few missing teeth were appreciated in both the cases.

Keywords

• Cleft lip
• cleft palate
• lip pits and Van der Woude syndrome