Novel biocompatible Cu2+-containing composite hydrogels based on bacterial cellulose and poly-1-vinyl-1,2,4-triazole

Ruslan Yu. Smyslov; Gennady P. Kopitsa; Yulia E. Gorshkova; Ksenia V. Ezdakova; Albert K. Khripunov; Alexandra V. Migunova; Natalia V. Tsvigun; Svetlana A. Korzhova; Artem I. Emel'yanov; Alexander S. Pozdnyakov

Smart Materials in Medicine (Jan 2022)

Novel biocompatible Cu2+-containing composite hydrogels based on bacterial cellulose and poly-1-vinyl-1,2,4-triazole

Ruslan Yu. Smyslov,
Gennady P. Kopitsa,
Yulia E. Gorshkova,
Ksenia V. Ezdakova,
Albert K. Khripunov,
Alexandra V. Migunova,
Natalia V. Tsvigun,
Svetlana A. Korzhova,
Artem I. Emel'yanov,
Alexander S. Pozdnyakov

Affiliations

Ruslan Yu. Smyslov: Institute of Macromolecular Compounds RAS, Saint Petersburg, 199004, Russia; Petersburg Nuclear Physics Institute NRC KI, 188300, Gatchina, Leningrad District, Russia; Corresponding author. Institute of Macromolecular Compounds RAS, Saint Petersburg 199004, Russia.
Gennady P. Kopitsa: Petersburg Nuclear Physics Institute NRC KI, 188300, Gatchina, Leningrad District, Russia
Yulia E. Gorshkova: Joint Institute for Nuclear Research, Dubna, Russia
Ksenia V. Ezdakova: Petersburg Nuclear Physics Institute NRC KI, 188300, Gatchina, Leningrad District, Russia
Albert K. Khripunov: Institute of Macromolecular Compounds RAS, Saint Petersburg, 199004, Russia
Alexandra V. Migunova: Saint Petersburg State University, Biological Faculty, Department of Microbiology, 199178, Saint-Petersburg, Russia
Natalia V. Tsvigun: Federal Scientific Research Centre “Crystallography and Photonics” of the Russian Academy of Sciences, Moscow, Russia
Svetlana A. Korzhova: A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 664033, Irkutsk, Russia
Artem I. Emel'yanov: A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 664033, Irkutsk, Russia
Alexander S. Pozdnyakov: A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 664033, Irkutsk, Russia

Journal volume & issue: Vol. 3
pp. 382 – 389

Abstract

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Novel composite hydrogels representing interpenetrating polymeric networks (IPN) have been synthesized and consisted of Gluconacetobacter xylinus cellulose (GxC) and poly-1-vinyl-1,2,4-triazole (PVT) with Cu2⁺. The composite hydrogels’ mesostructure has been studied from 1.6 nm to 2.5 μm by small-angle and ultra-small-angle neutron scattering methods. It has been found that IPN complexes have three types of inhomogeneities: GxC, PVT, and PVT complex with Cu2⁺. The amount of the absorbed ions can be tuned as confirmed by electron paramagnetic spectroscopy. Besides, three hierarchy levels of GxC remained in the supramolecular structure of composite hydrogels. Reveling structure formation in these composite hydrogels is essential in fabricating hybrid polymeric materials for regenerative medicine, involving antibacterial or antifungal applications.

Published in Smart Materials in Medicine

ISSN: 2590-1834 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology
Website: https://www.keaipublishing.com/en/journals/smart-materials-in-medicine/

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