The synthesis of new non-ionic surfactant 1-(2, 4-dinitrophenyl)-3-dodecanoylthiourea: An efficient candidate for drug deliveries and metabolism processes

Abstract

By utilizing the reaction of lauryl chloride, potassium thiocynate, and 2,4-dinitroaniline, the novel non-ionic surfactant 1-(2, 4-dinitrophenyl)-3-dodecanoylthiourea (DDT) was produced in high yield. Various spectroscopic techniques (1HNMR, 13CNMR, and UV-V) have been used to elucidate the chemical structure of DDT. Additionally, its electrochemical behaviour (electrochemical fate) was elucidated using a cyclic, square wave, and differential pulse voltammetry through a wide pH range. The limit of detection (LOD) and limit of quantification (LOQ) values of the compound were also determined using Square wave voltammetry (SWV). A fascinating fact observed is that the electroactive moieties in the compound are getting oxidized and reduced at a potential very close to 0.0 V, and the potential of the human body is 0.07 V, so the compound investigated can serve as an efficient candidate for the drug deliveries and metabolism processes.

Keywords

• Surfactant
• Electrochemical
• Drug deliveries
• Metabolism