Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2023)
Antimicrobial stewardship, procalcitonin testing, and rapid blood-culture identification to optimize sepsis care in critically ill adult patients: A quality improvement initiative
- Wendy I. Sligl,
- Justin Z. Chen,
- Xiaoming Wang,
- Cheyanne Boehm,
- Karen Fong,
- Katelynn Crick,
- Míriam Garrido Clua,
- Cassidy Codan,
- Tanis C. Dingle,
- Daniel Gregson,
- Connie Prosser,
- Hossein Sadrzadeh,
- Charles Yan,
- Guanmin Chen,
- Alena Tse-Chang,
- Daniel Garros,
- Christopher J. Doig,
- David Zygun,
- Dawn Opgenorth,
- John M. Conly,
- Sean M Bagshaw
Affiliations
- Wendy I. Sligl
- ORCiD
- Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada Division of Infectious Diseases, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
- Justin Z. Chen
- Division of Infectious Diseases, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
- Xiaoming Wang
- Health Services Statistical and Analytic Methods, Alberta Health Services, Edmonton, Alberta, Canada
- Cheyanne Boehm
- Pharmacy Services, Foothills Medical Centre, Alberta Health Services, Calgary, Alberta, Canada
- Karen Fong
- Pharmacy Services, University of Alberta Hospital, Alberta Health Services, Edmonton, Alberta, Canada
- Katelynn Crick
- Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada
- Míriam Garrido Clua
- Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada
- Cassidy Codan
- Department of Critical Care Medicine, Cumming School of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada
- Tanis C. Dingle
- Division of Diagnostic and Applied Microbiology, Department of Laboratory Medicine and Pathology, University of Alberta, and Alberta Precision Laboratories, Edmonton, Alberta, Canada
- Daniel Gregson
- Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada Department of Medicine, Cumming School of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada
- Connie Prosser
- Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada
- Hossein Sadrzadeh
- Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada
- Charles Yan
- ORCiD
- Institute of Health Economics, Edmonton, Alberta, Canada
- Guanmin Chen
- Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
- Alena Tse-Chang
- Division of Pediatric Infectious Diseases, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
- Daniel Garros
- ORCiD
- Division of Pediatric Critical Care, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
- Christopher J. Doig
- Department of Critical Care Medicine, Cumming School of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada
- David Zygun
- Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada
- Dawn Opgenorth
- ORCiD
- Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada
- John M. Conly
- Department of Medicine, Cumming School of Medicine, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada
- Sean M Bagshaw
- Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada Critical Care Strategic Clinical Network, Alberta Health Services, Edmonton, Alberta, Canada
- DOI
- https://doi.org/10.1017/ash.2023.183
- Journal volume & issue
-
Vol. 3
Abstract
We examined the effect of an antimicrobial stewardship program (ASP), procalcitonin testing and rapid blood-culture identification on hospital mortality in a prospective quality improvement project in critically ill septic adults. Secondarily, we have reported antimicrobial guideline concordance, acceptance of ASP interventions, and antimicrobial and health-resource utilization.
