239 Efficacy and toxicity of single agent immune checkpoint inhibitors among adults with cancer aged ≥80 years: a multicenter international cohort study

• Abdul Rafeh Naqash,
• Shravanti Macherla,
• Alessio Cortellini,
• Melissa Bersanelli,
• Sebastiano Buti,
• Raffaele Giusti,
• Marco Filetti,
• Paolo Marchetti,
• Andrea Botticelli,
• Domenico Mallardo,
• Thomas Marron,
• Douglas Johnson,
• Christopher Hoimes,
• Vito Vanella,
• Toni Choueiri,
• Paolo Ascierto,
• Ella Daniels,
• Haocan Song,
• Fei Ye,
• Tamara Sussman,
• Domenico Galetta,
• Anwaar Saeed,
• Annamaria Catino,
• Carlo Genova,
• Pamela Pizzutilo,
• Giuseppe Lamberti,
• David Pinato,
• Rebecca Irlmeier,
• Caroline Nebhan,
• Weijie Ma,
• Teja Ganta,
• Neha Debnath,
• Maluki Radford,
• Asrar Alahmadi,
• Akiva Diamond,
• Nikhil Ramaiya,
• Carolyn Presley,
• Dwight Owen,
• Sarah Abou Alaiwi,
• Amin Nassar,
• Chiara Casartelli,
• Maria Giovanna Dal Bello,
• Foteini Kalofonou

Affiliations

Abdul Rafeh Naqash

Division of Cancer Treatment And Diagnosis, National Cancer Institute, Bethesda, Maryland, USA

Shravanti Macherla

Aff1 0000 0001 2191 0423grid.255364.3Division of Hematology/OncologyEast Carolina University 600 Moye Boulevard 27834 Greenville NC USA

Alessio Cortellini

Division of Cancer, Department of Surgery and Cancer, Imperial College London, London, UK

Melissa Bersanelli

Medicine and Surgery Department, University of Parma, Parma, Italy

Sebastiano Buti

Medical Oncology Unit, University Hospital of Parma, Parma, Italy

Raffaele Giusti

Medical Oncology Unit, Sant`Andrea Hospital, Roma, Italy

Marco Filetti

Department of Clinical and Molecular Medicine, Oncology Unit, Sant’Andrea Hospital, Sapienza University of Rome, Roma, Italy

Paolo Marchetti

Department of Clinical and Molecular Medicine, Sapienza University of Rome, Roma, Italy

Andrea Botticelli

Aff6 grid.7841.aDepartment of Clinical and Molecular MedicineSant’Andrea Hospital, Sapienza University of Rome Rome Italy

Domenico Mallardo

Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy

Thomas Marron

3Icahn School of Medicine at Mount Sinai, New York, NY, USA

Douglas Johnson

Departments of General Medicine and Infectious Diseases, The Royal Melbourne Hospital, Parkville, Victoria, Australia

Christopher Hoimes

Aff4 0000 0004 0418 9795grid.473817.eCase Western Reserve University and University Hospitals Seidman Cancer Center Cleveland OH USA

Vito Vanella

Aff1 0000 0001 0807 2568grid.417893.0Unit of Melanoma, Cancer Immunotherapy and Development TherapeuticsIstituto Nazionale Tumori IRCCS Fondazione “G. Pascale” Via Mariano Semmola 80131 Naples Italy

Toni Choueiri

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA

Paolo Ascierto

6Istituto Nazionale Tumori IRCCS ‘Fondazione G. Pascale’, Naples, Italy

Ella Daniels

Melanoma and Renal Unit, Royal Marsden NHS Foundation Trust, London, UK

Haocan Song

Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Fei Ye

Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Tamara Sussman

School of Social Work, McGill University, Montreal, Quebec, Canada

Domenico Galetta

4 Division of Thoracic Surgery, IEO, European Institute of Oncology, IRCCS, Milano, Italy

Anwaar Saeed

Division of Medical Oncology, Kansas University Cancer Center, Kansas City, Kansas, USA

Annamaria Catino

Medical Thoracic Oncology Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy

Carlo Genova

Lung Cancer Unit, IRCCS Ospedal Policlinico San Martino, Genova, Italy

Pamela Pizzutilo

Thoracic Oncology Unit, Clinical Cancer Center IRCCS Istituto Tumori `Giovanni Paolo II`, Bari, Puglia, Italy

Giuseppe Lamberti

1Dana-Farber Cancer Institute, Boston, MA, USA

David Pinato

3Imperial College London, London, UK

Rebecca Irlmeier

Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Caroline Nebhan

1Vanderbilt University Medical Center, Nashville, TN, USA

Weijie Ma

3MD Anderson Cancer, Houston, TX, USA

Teja Ganta

4Icahn School of Medicine at Mount Sinai, New York, USA

Neha Debnath

4Icahn School of Medicine at Mount Sinai, New York, USA

Maluki Radford

5University of Kansas Cancer Center, Kansas City, KS, USA

Asrar Alahmadi

6Case Western Reserve University, Cleveland, USA

Akiva Diamond

6Case Western Reserve University, Cleveland, USA

Nikhil Ramaiya

6Case Western Reserve University, Cleveland, USA

Carolyn Presley

8The Ohio State University Comprehensive, Columbus, OH, USA

Dwight Owen

8The Ohio State University Comprehensive, Columbus, OH, USA

Sarah Abou Alaiwi

9Dana-Farber Cancer Center, Boston, MA, USA

Amin Nassar

9Dana-Farber Cancer Center, Boston, MA, USA

Chiara Casartelli

11University of Parma, Parma, Italy

Maria Giovanna Dal Bello

19IRCCS Ospedale Policlinico San Martino, Genova, Italy

Foteini Kalofonou

20Imperial College London, London, UK