The Application of External Ureteral Catheters in Children With Acute Kidney Injury Caused by Ceftriaxone-Induced Urolithiasis

Houwei Lin; Houwei Lin; Hongquan Geng; Hongquan Geng; Guofeng Xu; Guofeng Xu; Xiaoliang Fang; Xiaoliang Fang; Lei He; Lei He; Maosheng Xu; Maosheng Xu

doi:10.3389/fped.2020.00200

Frontiers in Pediatrics (Apr 2020)

The Application of External Ureteral Catheters in Children With Acute Kidney Injury Caused by Ceftriaxone-Induced Urolithiasis

Houwei Lin,
Houwei Lin,
Hongquan Geng,
Hongquan Geng,
Guofeng Xu,
Guofeng Xu,
Xiaoliang Fang,
Xiaoliang Fang,
Lei He,
Lei He,
Maosheng Xu,
Maosheng Xu

Affiliations

Houwei Lin: Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, China
Houwei Lin: Children's Urolithiasis Treatment Center of Chinese Health Committee, Shanghai, China
Hongquan Geng: Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, China
Hongquan Geng: Children's Urolithiasis Treatment Center of Chinese Health Committee, Shanghai, China
Guofeng Xu: Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, China
Guofeng Xu: Children's Urolithiasis Treatment Center of Chinese Health Committee, Shanghai, China
Xiaoliang Fang: Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, China
Xiaoliang Fang: Children's Urolithiasis Treatment Center of Chinese Health Committee, Shanghai, China
Lei He: Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, China
Lei He: Children's Urolithiasis Treatment Center of Chinese Health Committee, Shanghai, China
Maosheng Xu: Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, China
Maosheng Xu: Children's Urolithiasis Treatment Center of Chinese Health Committee, Shanghai, China

DOI: https://doi.org/10.3389/fped.2020.00200
Journal volume & issue: Vol. 8

Abstract

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Objective: To evaluate our use of external ureteral catheters in children with acute kidney injury (AKI) resulting from ceftriaxone-induced urolithiasis.Methods: From July 2010 to June 2015, a series of 15 children, including 12 males and 3 females, were referred to our department. All of them were diagnosed of post-renal AKI and underwent emergent hospitalization. Evaluation of serum electrolytes, creatinine (Cr), blood urea nitrogen (BUN), complete blood count, and blood gas analysis were completed in each child both before they were admitted, and again after surgery. Bilateral externalized ureteral catheters were placed cystoscopically in each of these patients. The composition of collected calculi was analyzed by infrared spectrography.Results: Bilateral externalized ureteral catheters were placed successfully in all patients. There were no procedure-related complications. Two days after catheter placement, the levels of serum Cr and BUN had improved in all patients, and these levels were noted to be significantly lower than before catheterization (P < 0.001). Infrared spectrography demonstrated that the primary composition of all calculi collected was ceftriaxone. No recurrent AKI or renal deterioration was detected during the follow-up which ranged from 3 to 8 years.Conclusions: These results show that short-term external ureteral catheters can be effectively utilized in children with AKI caused by ceftriaxone-induced urolithiasis. We recommend this procedure as a viable replacement to indwelling stents in patients with bilateral ureteral stones.

Published in Frontiers in Pediatrics

ISSN: 2296-2360 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Pediatrics
Website: http://journal.frontiersin.org/journal/pediatrics

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