Intermembrane crosstalk drives inner-membrane protein organization in Escherichia coli

Patrice Rassam; Kathleen R. Long; Renata Kaminska; David J. Williams; Grigorios Papadakos; Christoph G. Baumann; Colin Kleanthous

doi:10.1038/s41467-018-03521-4

Nature Communications (Mar 2018)

Intermembrane crosstalk drives inner-membrane protein organization in Escherichia coli

Patrice Rassam,
Kathleen R. Long,
Renata Kaminska,
David J. Williams,
Grigorios Papadakos,
Christoph G. Baumann,
Colin Kleanthous

Affiliations

Patrice Rassam: Department of Biochemistry, University of Oxford
Kathleen R. Long: Department of Biology, University of York
Renata Kaminska: Department of Biochemistry, University of Oxford
David J. Williams: Department of Biology, University of York
Grigorios Papadakos: Department of Biochemistry, University of Oxford
Christoph G. Baumann: Department of Biology, University of York
Colin Kleanthous: Department of Biochemistry, University of Oxford

DOI: https://doi.org/10.1038/s41467-018-03521-4
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 8

Abstract

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Outer membrane proteins (OMPs) in Gram-negative bacteria have restricted lateral mobility. Here, Rassam et al. show that the bacteriocin ColE9, via its interactions with OMPs, imposes this restricted mobility on the inner membrane proteins of the Tol-Pal complex.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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