HISTOPATHOLOGIC CHANGES AT THE HYPOTHALAMIC, ADRENAL AND THYMIC NUCLEUS ARCUATUS IN RATS TREATED WITH MONOSODIUM GLUTAMATE

Abstract

The study consists of 100 patients who underwent surgery and were treated at the Surgical Clinic of Nis Clinical Centre. The patients were divided into two groups: the first one included 50 patients subjected to surgery with the use of the Shouldice operative technique (control group) and the second one included 50 patients who underwent surgery with the use of the Lichtenstein operative technique (experimental group). In these 100 patients, the pain score was examined on the basis of Visual Analogous Score (VAS) or using Verbal Pain Score (VPS). For statistical analysis we used the T – test for two large independent samples, which was later presented on graphs, tables and diagram. The pain score was observed from the first to the seventh day, and then on the tenth, fifteenth, twentieth, thirtieth, two months and one year after. The examination results showed a significantly lower pain score in patients who underwent surgery with the use of Lichtenstein technique.

Keywords

• monosodium glutamate
• nucleus arcuatus
• adrenal glands
• thymus