Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple)

• Laurent Batiste,
• Andrea Unzue,
• Aymeric Dolbois,
• Fabrice Hassler,
• Xuan Wang,
• Nicholas Deerain,
• Jian Zhu,
• Dimitrios Spiliotopoulos,
• Cristina Nevado,
• Amedeo Caflisch

Affiliations

Laurent Batiste

Department of Biochemistry, University of Zurich, Zürich, Switzerland

Andrea Unzue

Department of Chemistry, University of Zurich, Zürich, Switzerland

Aymeric Dolbois

Department of Chemistry, University of Zurich, Zürich, Switzerland

Fabrice Hassler

Department of Chemistry, University of Zurich, Zürich, Switzerland

Xuan Wang

Department of Biochemistry, University of Zurich, Zürich, Switzerland

Nicholas Deerain

Department of Biochemistry, University of Zurich, Zürich, Switzerland

Jian Zhu

Department of Biochemistry, University of Zurich, Zürich, Switzerland

Dimitrios Spiliotopoulos

Department of Biochemistry, University of Zurich, Zürich, Switzerland

Cristina Nevado

Department of Chemistry, University of Zurich, Zürich, Switzerland

Amedeo Caflisch

Department of Biochemistry, University of Zurich, Zürich, Switzerland