Clinical effect analysis of different surgical treatment of primary pterygium

Abstract

AIM: To compare and analyze the clinical treatment effect of primary pterygium with amniotic membrane transplantation, autologous corneal limbus stem cell transplantation and intraoperative application of 0.2g/L mitomycin C. METHODS: Retrospective analysis of 232 patients who were underwent primary pterygium surgery was performed. Eighty-two cases were treated with amniotic membrane transplantation, 90 with autologous corneal limbus stem cell transplantation, and 60 with intraoperative application of 0.2g/L mitomycin C. The postoperative recurrence and complications of three operative methods were compared. RESULTS: The recurrence rate of autologous corneal limbus stem cell transplantation and intraoperative application of 0.2g/L mitomycin C was lower than that of amniotic membrane transplantation(PP>0.05). Corneal epithelium defect, tears and photophobia were higher in 0.2g/L mitomycin C group(PP>0.05). Conjunctival congestion and subconjunctival hemorrhage in three groups had no statistical difference(P>0.05). CONCLUSION: Compared with other two operative methods,autologous corneal limbus stem cell transplantation for primary pterygium has the advantages of lower recurrence rate and less complications.

Keywords

• pterygium
• amniotic membrane transplantation
• autologous corneal limbus stem cell transplantation
• mitomycin C