Cognitive Function in Multiple Sclerosis: A Subcortical Pattern of Neuropsychological Impairment?

Carlo Caltagirone; Giovanni Augusto Carlesimo; Lucia Fadda; Sabina Roncacci

doi:10.3233/BEN-1991-4301

Behavioural Neurology (Jan 1991)

Cognitive Function in Multiple Sclerosis: A Subcortical Pattern of Neuropsychological Impairment?

Carlo Caltagirone,
Giovanni Augusto Carlesimo,
Lucia Fadda,
Sabina Roncacci

Affiliations

Carlo Caltagirone: Neurologic Clinic, 2nd University of Rome, Ospedale S. Eugenio, P. le dell'Umanesimo, 10, 00144 Roma, Italy
Giovanni Augusto Carlesimo: Neurologic Clinic, 2nd University of Rome, Ospedale S. Eugenio, P. le dell'Umanesimo, 10, 00144 Roma, Italy
Lucia Fadda: Neurologic Clinic, 2nd University of Rome, Ospedale S. Eugenio, P. le dell'Umanesimo, 10, 00144 Roma, Italy
Sabina Roncacci: Neurologic Clinic, 2nd University of Rome, Ospedale S. Eugenio, P. le dell'Umanesimo, 10, 00144 Roma, Italy

DOI: https://doi.org/10.3233/BEN-1991-4301
Journal volume & issue: Vol. 4, no. 3
pp. 129 – 141

Abstract

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In order to evaluate cognitive impairment in multiple sclerosis (MS) neuropsychological tests were administered to 25 patients with clinically definite disease. Four (16%) showed diffuse cognitive impairment, whereas the others, compared with controls showed a specific deficit on tests known to be sensitive to frontal lobe damage. These results are interpreted in the light of current hypotheses relating to subcortical contributions in cognition.

Published in Behavioural Neurology

ISSN: 0953-4180 (Print); 1875-8584 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: https://onlinelibrary.wiley.com/journal/3037

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