Nature Communications (Jan 2016)
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
- Janko Kajtez,
- Anastasia Solomatina,
- Maja Novak,
- Bruno Polak,
- Kruno Vukušić,
- Jonas Rüdiger,
- Gheorghe Cojoc,
- Ana Milas,
- Ivana Šumanovac Šestak,
- Patrik Risteski,
- Federica Tavano,
- Anna H. Klemm,
- Emanuele Roscioli,
- Julie Welburn,
- Daniela Cimini,
- Matko Glunčić,
- Nenad Pavin,
- Iva M. Tolić
Affiliations
- Janko Kajtez
- Max Planck Institute of Molecular Cell Biology and Genetics
- Anastasia Solomatina
- Max Planck Institute of Molecular Cell Biology and Genetics
- Maja Novak
- Department of Physics, Faculty of Science, University of Zagreb
- Bruno Polak
- Max Planck Institute of Molecular Cell Biology and Genetics
- Kruno Vukušić
- Division of Molecular Biology, Ruđer Bošković Institute
- Jonas Rüdiger
- Max Planck Institute of Molecular Cell Biology and Genetics
- Gheorghe Cojoc
- Max Planck Institute of Molecular Cell Biology and Genetics
- Ana Milas
- Division of Molecular Biology, Ruđer Bošković Institute
- Ivana Šumanovac Šestak
- Max Planck Institute of Molecular Cell Biology and Genetics
- Patrik Risteski
- Division of Molecular Biology, Ruđer Bošković Institute
- Federica Tavano
- Max Planck Institute of Molecular Cell Biology and Genetics
- Anna H. Klemm
- Max Planck Institute of Molecular Cell Biology and Genetics
- Emanuele Roscioli
- Department of Biological Sciences, Virginia Tech
- Julie Welburn
- Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Michael Swann Building, Max Born Crescent
- Daniela Cimini
- Department of Biological Sciences, Virginia Tech
- Matko Glunčić
- Department of Physics, Faculty of Science, University of Zagreb
- Nenad Pavin
- Department of Physics, Faculty of Science, University of Zagreb
- Iva M. Tolić
- Max Planck Institute of Molecular Cell Biology and Genetics
- DOI
- https://doi.org/10.1038/ncomms10298
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 11
Abstract
During metaphase, k-fibre microtubules exert force on kinetochores, but there are also non-kinetochore microtubules close to kinetochores without a known function. Here the authors show that these microtubules, which they call bridging fibres, balance interkinetochore tension by bridging sister k-fibres.
