ASSOCIATION OF MARITAL STATUS, EARLY MARRIAGE AND PARITY WITH FIBROADENOMA

Abstract

Objective: To evaluate the association of marital status, early marriage and parity with fibroadenoma patients at a tertiary care hospital of Pakistan. Study Design: Case control study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Jul 2015 to Jan 2016. Methodology: A total of 156 cases were included which were diagnosed histologically for fibroadenoma. Similarly 152 controls were inducted which were matched for age and body mass index. The case and control groups were interviewed about exposure of risk factors. Results: All the patients were females. The mean age of case group was 23.71 ± 3.81 and mean age of control group was 23.99 ± 3.95 (p-value=0.544). There was no significant difference in body mass index of two groups (p-value=0.756). Marital status (OR=1.807 95% CI 1.074-3.039) and nulliparous status (OR=2.372 95% CI 1.398- 4.024) were associated with development of fibroadenoma. However early marriage did not have any significant relation with fibroadenoma (OR=0.928 CI 95% 0.511-1.683). Conclusions: Fibroadenoma is more likely to develop in unmarried and nulliparous women however early marriage may not be related to its development.

Keywords

• fibroadenoma
• female hormones
• risk factor