Research Progress of Metastasis Related Factors in Gastric Cancer

Abstract

Metastasis is the main manifestation of advanced gastric cancer patients and the main cause of treatment failure.Some gastric cancer metastasis related factors promote or inhibit gastric cancer metastasis by regulating epithelial-mesenchymal transition, adhesion, migration, invasion, proliferation and angiogenesis.This article aims to provide a view of the effects and potential molecular mechanisms of gastric cancer metastasis related factors in different stages of gastric cancer metastasis, clarify their mechanisms of regulating gastric cancer metastasis and potential therapeutic targets, provide new detection methods for gastric cancer metastasis and new treatment options for patients with metastasis gastric cancer.

Keywords

• stomach cancer
• neoplasm metastasis
• metastasis related factors