Regioselective synthesis of bicyclic 1,3,5-triazepine system starting from tetrachloro-2-aza-1,3-butadienes

Abstract

Readily available tetrachloro-2-aza-1,3-butadienes enter into directed cyclocondensation reaction with N-phenyl-1,2-cyclopentanediamine which leads to regioselective cyclopentane annulation by the 1,3,5-triazepine. The formation of the 1,3,5-triazepine derivatives was confirmed proved by 1H- and 13C-NMR spectral study, elemental analysis and, in one case, single-crystal x-ray crystallographic study.

Keywords

• Tetrachloro-2-aza-1
• 3-butadienes
• N-phenyl-1
• 2cyclopentanediamine
• 1
• 3
• 5-triazepine
• regioselective annulation