Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome

• Xiaoping Hong,
• Xiaoping Hong,
• Shuhui Meng,
• Donge Tang,
• Tingting Wang,
• Liping Ding,
• Haiyan Yu,
• Heng Li,
• Dongzhou Liu,
• Yong Dai,
• Min Yang

Affiliations

Xiaoping Hong

Department of Rheumatology and Immunology, Southern Medical University, Nanfang Hospital, Guangzhou, China

Xiaoping Hong

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Shuhui Meng

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Donge Tang

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Tingting Wang

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Liping Ding

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Haiyan Yu

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Heng Li

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Dongzhou Liu

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Yong Dai

Department of Rheumatology and Immunology, Department of Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University, The First Affiliated Hospital Southern University of Science and Technology), Shenzhen, China

Min Yang

Department of Rheumatology and Immunology, Southern Medical University, Nanfang Hospital, Guangzhou, China