Determination of knee cartilage volume and surface area in beagle dogs: a pilot study

Abstract

Abstract Background The objective of this study was to determine the cartilage volume and surface area of male and female Beagle dog knees using 3D (3 dimensional) reconstructed MRI images. Methods Six Beagle Dogs (Canis familiaris) (3 males and 3 females) of 10-18 months old and weighing between 7.2 and 17.1 kg underwent a MRI evaluation of both knees. The data acquired allowed a 3D reconstruction of the knee and measurement of the cartilage volume and surface area. Results Mean knee cartilage volume (averaged over the right and left knees) of animals between 7.2 and 17.1 kg ranged from 319.7 to 647.3 mm3; while the mean knee cartilage surface area ranged from 427.14 to 757.2 mm2. There was evidence of both knee volume and surface area increasing linearly with animal bodyweight. Conclusions The cartilage volume and surface area of the Beagle dog appears to correlate significantly with body weight. This study provides a reference base for future studies investigating cartilage related pathology such as osteoarthritis.

Keywords

• Beagle dogs
• MRI
• Cartilage
• Surface area
• Volume