TUBERCULOSIS IN THE PRESENCE OF CHRONIC ALCOHOL INTOXICATION: MORTALITY STRUCTURE, DEATH CAUSES, AND MORPHOLOGICAL FEATURES

Abstract

The rate of caseous pneumonia and disseminated pulmonary tuberculosis in the structure of mortality from tuberculosis concurrent with chronic alcoholism or alcoholic disease was found to be 3.4 and 1.3 times greater than that of these forms in tuberculosis without alcohol intoxication. Alcohol-induced multiple organ failure was a cause of death in 21%. Toxic damage of respiratory organs with alcohol and its metabolites is characterized by circulatory disturbance in the microcirculatory system, increased wall vascular permeability, plasmorrhagia, interalveolar septal collagenization with vascular desolation in the microcirculatory bed, which underlies the histogenesis of pulmonary alcoholic disease.

Keywords

• tuberculosis
• chronic alcoholism
• postmortem examinations
• alcoholic lung disease