Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves

Shalom Nwodo Chinedu; Franklyn Nonso Iheagwam; Boluwatife Taiwo Makinde; Babajide Oladipo Thorpe; Opeyemi Christianah Emiloju

Data in Brief (Oct 2018)

Data on in vivo antioxidant, hypolipidemic and hepatoprotective potential of Thaumatococcus daniellii (Benn.) Benth leaves

Shalom Nwodo Chinedu,
Franklyn Nonso Iheagwam,
Boluwatife Taiwo Makinde,
Babajide Oladipo Thorpe,
Opeyemi Christianah Emiloju

Affiliations

Shalom Nwodo Chinedu: Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Covenant University Public Health and Wellness Research Cluster (CUPHWERC), Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Corresponding authors.
Franklyn Nonso Iheagwam: Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Covenant University Public Health and Wellness Research Cluster (CUPHWERC), Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Corresponding authors.
Boluwatife Taiwo Makinde: Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria
Babajide Oladipo Thorpe: Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria
Opeyemi Christianah Emiloju: Department of Biochemistry, College of Science and Technology, Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria; Covenant University Public Health and Wellness Research Cluster (CUPHWERC), Covenant University, P.M.B. 1023, Canaanland, Ota, Ogun State, Nigeria

Journal volume & issue: Vol. 20
pp. 364 – 370

Abstract

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This data article reports on the in vivo biochemical activity of ethanolic extract of Thaumatococcus daniellii (Benn.) Benth leaves (ETD) in male Wistar rats at an oral dose of 500–1500 mg/kg daily for 14 days. Control groups were administered distilled water and Vitamin C (10 mg/kg; b.wt). Indices of oxidative stress, dyslipidemia, liver injury and liver pathology were estimated in the plasma and organs after the investigation period. Oral treatment with ETD increased organ superoxide dismutase (SOD) activity, renal reduced glutathione (GSH) and plasma high density lipoprotein (HDL) concentrations while reducing plasma alanine transaminase (ALT) activity, plasma cholesterol (CHOL), bilirubin (DBIL) and organ malondialdehyde (MDA) concentrations (P<0.05). Data was supported by histological report showing no pathologic abnormality. This data indicate ethanolic extract of T. daniellii leaves shows antioxidant, hypolipidemic and hepatoprotective potential. Keywords: Thaumatococcus daniellii, in vivo, Oxidative stress, Antioxidant, Liver injury, Hypolipidemic

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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