Frontiers in Pediatrics (Jun 2024)

Case Report: Chronic pancreatitis in children as the cumulative effect of bilio-pancreatic abnormalities and genetic mutations

  • Francesca Destro,
  • Eleonora Durante,
  • Raffaele Salerno,
  • Alessandro Campari,
  • Milena Meroni,
  • Veronica Diotto,
  • Marco Brunero,
  • Gloria Pelizzo,
  • Gloria Pelizzo

DOI
https://doi.org/10.3389/fped.2024.1393891
Journal volume & issue
Vol. 12

Abstract

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Pancreatitis, in general, is a high-morbidity condition. Genetic conditions and anatomic variants are sometimes seen, especially in children, where biliary etiologies and alcohol are less common than in adults. The decision to intervene, the combined operative-endoscopic strategy, and the timing pose unique challenges. We report the case of a 10-year-old boy with PRSS1 mutation and pancreatic duct duplication, discussing the management and reviewing the recent reports in the Literature.

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