European Journal of Case Reports in Internal Medicine (Dec 2020)

Pulmonary Hypertension in COVID-19 Pneumoniae: It Is Not Always as It Seems

  • Maria Cristina Pasqualetto,
  • Maria Domenica Sorbo,
  • Maria Vitiello,
  • Chiara Ferrara,
  • Moreno Scevola,
  • Fabio Pantalone,
  • Fabio Gelain,
  • Claudio Aloi,
  • Manuele Nizzetto,
  • Fausto Rigo

DOI
https://doi.org/10.12890/2020_002160

Abstract

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A patient affected by COVID-19 pneumonia may develop pulmonary hypertension (PH) and secondary right ventricular (RV) involvement, due to lung parenchymal and interstitial damage and altered pulmonary haemodynamics, even in non-advanced phases of the disease. This is a consequence of hypoxic vasoconstriction of the pulmonary circulation, the use of positive end-expiratory pressure (PEEP) in mechanical ventilation, pulmonary endothelial injury, and local inflammatory thrombotic and/or thromboembolic processes. We report the case of a young man admitted with a diagnosis of COVID-19 pneumoniae with PH unrelated to viral infection and in whom partial anomalous pulmonary venous drainage (PAPVD) was eventually diagnosed.

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