BMJ Open (May 2022)
Effects of temporarily suspending low-dose methotrexate treatment for 2 weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory conditions: protocol for a multicentre randomised controlled trial and nested mechanistic substudy (Vaccine Response On/Off Methotrexate (VROOM) study)
- Abhishek Abhishek,
- Daniel M Altmann,
- Lucy Eldridge,
- James Bluett,
- Anne Francis,
- Ines Rombach,
- Duncan Appelbe,
- Hywel C Williams,
- Vicki S Barber,
- Jonathan Alistair Cook,
- Ana M Valdes,
- Laura Coates,
- Lucy Cureton,
- Patrick Julier,
- Nicholas Peckham,
- Jonathan Nguyen-Van-Tam,
- RJ Boyton,
- Áine McKnight
Affiliations
- Abhishek Abhishek
- Academic Rheumatology, University of Nottingham, Nottingham, UK
- Daniel M Altmann
- Department of Immunology and Inflammation, Imperial College London, London, UK
- Lucy Eldridge
- NDORMS, University of Oxford, Oxford, UK
- James Bluett
- Manchester Academic Health Science Centre, Manchester, UK
- Anne Francis
- NDORMS, University of Oxford, Oxford, UK
- Ines Rombach
- Oxford Clinical Trials Unit, Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford Nuffield, Oxford, UK
- Duncan Appelbe
- NDORMS, University of Oxford, Oxford, UK
- Hywel C Williams
- Population and Lifespan Health, University of Nottingham, Nottingham, UK
- Vicki S Barber
- NDORMS, University of Oxford, Oxford, UK
- Jonathan Alistair Cook
- NDORMS, University of Oxford, Oxford, UK
- Ana M Valdes
- Academic Rheumatology, University of Nottingham, Nottingham, UK
- Laura Coates
- NDORMS, University of Oxford, Oxford, UK
- Lucy Cureton
- NDORMS, University of Oxford, Oxford, UK
- Patrick Julier
- NDORMS, University of Oxford, Oxford, UK
- Nicholas Peckham
- NDORMS, University of Oxford, Oxford, UK
- Jonathan Nguyen-Van-Tam
- Population and Lifespan Health, University of Nottingham, Nottingham, UK
- RJ Boyton
- Department of Infectious Diseases, Imperial College London, London, UK
- Áine McKnight
- Blizard Institute, Centre for Genomics and Child Health, Queen Mary University of London, London, UK
- DOI
- https://doi.org/10.1136/bmjopen-2022-062599
- Journal volume & issue
-
Vol. 12,
no. 5
Abstract
No abstracts available.