Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors

• Peng-Hsun Chase Chen,
• Xuejiao Shirley Guo,
• Hanyuan Eric Zhang,
• Gopal K. Dubey,
• Zhi Zachary Geng,
• Carol A. Fierke,
• Shiqing Xu,
• J. Trae Hampton,
• Wenshe Ray Liu

Affiliations

Peng-Hsun Chase Chen

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States

Xuejiao Shirley Guo

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States

Hanyuan Eric Zhang

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States

Gopal K. Dubey

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States

Zhi Zachary Geng

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States

Carol A. Fierke

Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States

Shiqing Xu

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States

J. Trae Hampton

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States

Wenshe Ray Liu

Texas A&M Drug Discovery Center and Department of Chemistry, Texas A&M University, College Station, Texas, United States