Hansen's disease in association with immune reconstitution inflammatory syndrome

Abstract

Immune reconstitution inflammatory syndrome is characterized by a paradoxical worsening of an existing infection or disease process, soon after initiation of highly active antiretroviral therapy. The first case of leprosy presenting as immune reconstitution inflammatory syndrome was published in 2003. Here we report a case of Hansen's disease borderline tuberculoid presenting with type 1 lepra reaction 5 months after initiation of highly active antiretroviral therapy.

Keywords

• Borderline tuberculoid Hansen's disease
• HIV infection
• immune reconstitution inflammatory syndrome
• type 1 lepra reaction