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Disease Models & Mechanisms
(Nov 2023)
A genetic mosaic mouse model illuminates the pre-malignant progression of basal-like breast cancer
Jianhao Zeng,
Shambhavi Singh,
Xian Zhou,
Ying Jiang,
Eli Casarez,
Kristen A. Atkins,
Kevin A. Janes,
Hui Zong
Affiliations
Jianhao Zeng
Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA 22908, USA
Shambhavi Singh
Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22908, USA
Xian Zhou
Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA 22908, USA
Ying Jiang
Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA 22908, USA
Eli Casarez
Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA 22908, USA
Kristen A. Atkins
Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
Kevin A. Janes
Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22908, USA
Hui Zong
Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, VA 22908, USA
DOI
https://doi.org/10.1242/dmm.050219
Journal volume & issue
Vol. 16, no. 11
Abstract
Read online
No abstracts available.
Keywords
mouse genetic mosaic model
basal-like breast cancer
brca1
pre-malignancy
spatiotemporal analysis of tumor initiation
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