Caspian Journal of Internal Medicine (Jul 2021)

Refractory hypoglycemia induced by a duodenal wall gastrointestinal stromal tumor: A case report

  • Foolad Eghbali,
  • Reza Karami

Journal volume & issue
Vol. 12, no. Supplement 2
pp. 447 – 450

Abstract

Read online

Background: Tumor-associated hypoglycemia can be caused by non-islet cell tumors including gastrointestinal stromal tumor (GIST) which is a rare paraneoplastic syndrome that leads to the release of insulin-like growth factor-2 (IGF-2). Case Presentation: We report the case of a 45-year old woman who was admitted to our hospital with refractory hypoglycemic episodes. We found normal serum insulin and c-peptide level and abdominal CT-scan showed a small duodenal wall lesion suggesting insulinoma. After tumor resection, hypoglycemia symptoms were recovered, but the pathological findings demonstrated the lesion was GIST. Conclusion: In a small gastrointestinal lesion with hypoglycemic symptoms we should consider IGF-II secreting GIST in addition to insulinoma.

Keywords