Trans-synaptic degeneration of the optic radiation from optic nerve atrophy

Shingo Kihira, MD; Anthony C. Arnold, MD; Puneet S. Pawha, MD; Pablo Villablanca, MD; Kambiz Nael, MD

Radiology Case Reports (Apr 2021)

Trans-synaptic degeneration of the optic radiation from optic nerve atrophy

Shingo Kihira, MD,
Anthony C. Arnold, MD,
Puneet S. Pawha, MD,
Pablo Villablanca, MD,
Kambiz Nael, MD

Affiliations

Shingo Kihira, MD: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Anthony C. Arnold, MD: Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Puneet S. Pawha, MD: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Pablo Villablanca, MD: Department of Radiological Sciences, David Geffen School of Medicine at University of California Los Angeles, CA, USA
Kambiz Nael, MD: Department of Radiological Sciences, David Geffen School of Medicine at University of California Los Angeles, CA, USA; Corresponding author.

Journal volume & issue: Vol. 16, no. 4
pp. 855 – 857

Abstract

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Fourty-seven-year-old woman with 5-year history of progressive decreased left eye vision. Optical coherence tomography showed optic nerve atrophy (left > right) and brain MRI revealed T2 hyperintense signal along the course of left optic radiations. We present a case of a trans-synaptic degeneration of the optic radiation in a patient with confirmed optic atrophy. Trans-synaptic degeneration of the optic radiation without associated infarct or inflammatory disease has not been reported before in patients with optic atrophy.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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Abstract

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