Scientific Data (Jan 2023)
Deep phenotyping and genomic data from a nationally representative study on dementia in India
- Jinkook Lee,
- Sarah Petrosyan,
- Pranali Khobragade,
- Joyita Banerjee,
- Sandy Chien,
- Bas Weerman,
- Alden Gross,
- Peifeng Hu,
- Jennifer A. Smith,
- Wei Zhao,
- Leon Aksman,
- Urvashi Jain,
- G. S. Shanthi,
- Ravi Kurup,
- Aruna Raman,
- Sankha Shubhra Chakrabarti,
- Indrajeet Singh Gambhir,
- Mathew Varghese,
- John P. John,
- Himanshu Joshi,
- Parvaiz A. Koul,
- Debabrata Goswami,
- Arunansu Talukdar,
- Rashmi Ranjan Mohanty,
- Y. Sathyanarayana Raju Yadati,
- Mekala Padmaja,
- Lalit Sankhe,
- Chhaya Rajguru,
- Monica Gupta,
- Govind Kumar,
- Minakshi Dhar,
- Jorge Jovicich,
- Andrea Ganna,
- Mary Ganguli,
- Prasun Chatterjee,
- Sunny Singhal,
- Rishav Bansal,
- Swati Bajpai,
- Gaurav Desai,
- Swaroop Bhatankar,
- Abhijith R. Rao,
- Palanimuthu T. Sivakumar,
- Krishna Prasad Muliyala,
- Preeti Sinha,
- Santosh Loganathan,
- Erik Meijer,
- Marco Angrisani,
- Jung Ki Kim,
- Sharmistha Dey,
- Perianayagam Arokiasamy,
- David E. Bloom,
- Arthur W. Toga,
- Sharon L. R. Kardia,
- Kenneth Langa,
- Eileen M. Crimmins,
- Aparajit B. Dey
Affiliations
- Jinkook Lee
- Center for Economic and Social Research, University of Southern California
- Sarah Petrosyan
- Center for Economic and Social Research, University of Southern California
- Pranali Khobragade
- Center for Economic and Social Research, University of Southern California
- Joyita Banerjee
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- Sandy Chien
- Center for Economic and Social Research, University of Southern California
- Bas Weerman
- Center for Economic and Social Research, University of Southern California
- Alden Gross
- Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health
- Peifeng Hu
- Division of Geriatric Medicine, University of California, Los Angeles
- Jennifer A. Smith
- Department of Epidemiology, School of Public Health, University of Michigan
- Wei Zhao
- Department of Epidemiology, School of Public Health, University of Michigan
- Leon Aksman
- Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California
- Urvashi Jain
- Department of Economics, Finance and Real Estate, University of South Alabama
- G. S. Shanthi
- Department of Geriatric Medicine, Madras Medical College
- Ravi Kurup
- Department of Medicine, Government Medical College
- Aruna Raman
- Department of Medicine, Government Medical College
- Sankha Shubhra Chakrabarti
- Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University
- Indrajeet Singh Gambhir
- Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University
- Mathew Varghese
- Department of Psychiatry, National Institute of Mental Health and Neurosciences
- John P. John
- Department of Psychiatry, National Institute of Mental Health and Neurosciences
- Himanshu Joshi
- Department of Psychiatry, National Institute of Mental Health and Neurosciences
- Parvaiz A. Koul
- Department of Internal and Pulmonary Medicine, Sher-e-Kashmir Institute of Medical Sciences
- Debabrata Goswami
- Department of Medicine, Guwahati Medical College
- Arunansu Talukdar
- Department of Geriatric Medicine, Medical College
- Rashmi Ranjan Mohanty
- Department of Medicine, All India Institute of Medical Sciences
- Y. Sathyanarayana Raju Yadati
- Department of Medicine, Nizam’s Institute of Medical Sciences
- Mekala Padmaja
- Department of Medicine, Nizam’s Institute of Medical Sciences
- Lalit Sankhe
- Department of Community Medicine, Grant Medical College and J.J. Hospital
- Chhaya Rajguru
- Department of Community Medicine, Grant Medical College and J.J. Hospital
- Monica Gupta
- Department of General Medicine, Government Medical College and Hospital
- Govind Kumar
- Department of Medicine Indira Gandhi Institute of Medical Sciences
- Minakshi Dhar
- Department of Medicine, All India Institute of Medical Sciences
- Jorge Jovicich
- Center for Mind/Brain Sciences, University of Trento
- Andrea Ganna
- Finnish Institute of Molecular Medicine, University of Helsinki
- Mary Ganguli
- Department of Psychiatry, University of Pittsburgh
- Prasun Chatterjee
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- Sunny Singhal
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- Rishav Bansal
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- Swati Bajpai
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- Gaurav Desai
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- Swaroop Bhatankar
- Institute of Psychological Health
- Abhijith R. Rao
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- Palanimuthu T. Sivakumar
- Department of Psychiatry, National Institute of Mental Health and Neurosciences
- Krishna Prasad Muliyala
- Department of Psychiatry, National Institute of Mental Health and Neurosciences
- Preeti Sinha
- Department of Psychiatry, National Institute of Mental Health and Neurosciences
- Santosh Loganathan
- Department of Psychiatry, National Institute of Mental Health and Neurosciences
- Erik Meijer
- Center for Economic and Social Research, University of Southern California
- Marco Angrisani
- Center for Economic and Social Research, University of Southern California
- Jung Ki Kim
- School of Gerontology, University of Southern California
- Sharmistha Dey
- Department of Biophysics, All India Institute of Medical Sciences
- Perianayagam Arokiasamy
- Department of Development Studies, International Institute for Population Sciences
- David E. Bloom
- Department of Global Health and Population, Harvard T.H. Chan School of Public Health
- Arthur W. Toga
- Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California
- Sharon L. R. Kardia
- Department of Epidemiology, School of Public Health, University of Michigan
- Kenneth Langa
- Department of Internal Medicine, University of Michigan
- Eileen M. Crimmins
- School of Gerontology, University of Southern California
- Aparajit B. Dey
- Department of Geriatric Medicine, All India Institute of Medical Sciences
- DOI
- https://doi.org/10.1038/s41597-023-01941-6
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 12
Abstract
Abstract The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is a nationally representative in-depth study of cognitive aging and dementia. We present a publicly available dataset of harmonized cognitive measures of 4,096 adults 60 years of age and older in India, collected across 18 states and union territories. Blood samples were obtained to carry out whole blood and serum-based assays. Results are included in a venous blood specimen datafile that can be linked to the Harmonized LASI-DAD dataset. A global screening array of 960 LASI-DAD respondents is also publicly available for download, in addition to neuroimaging data on 137 LASI-DAD participants. Altogether, these datasets provide comprehensive information on older adults in India that allow researchers to further understand risk factors associated with cognitive impairment and dementia.
