Generation of a control induced pluripotent stem cell line (SDUCHi001-A) from a healthy male donor

Chunmiao Li; Fengjuan Zhang; Xiaoyi Wang; Mengmeng Chen

Stem Cell Research (Jun 2024)

Generation of a control induced pluripotent stem cell line (SDUCHi001-A) from a healthy male donor

Chunmiao Li,
Fengjuan Zhang,
Xiaoyi Wang,
Mengmeng Chen

Affiliations

Chunmiao Li: Department of Blood Transfusion, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong 250022, China
Fengjuan Zhang: Weifang Municipal Center for Disease Control and Prevention, Weifang, Shandong 261061, China
Xiaoyi Wang: Institute of Molecular Medicine and Genetics, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China
Mengmeng Chen: Department of Clinical Laboratory, Children’s Hospital Affiliated to Shandong University, Jinan, Shandong 250022, China; Corresponding author.

Journal volume & issue: Vol. 77
p. 103433

Abstract

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An induced pluripotent stem cell (iPSC) line (SDUCHi001-A) was established using peripheral blood mononuclear cells (PBMCs) from a healthy 6 years old boy. Reprogramming of the PBMCs was achieved through non-integrating delivery of OCT4, SOX2, KFL4, BCL-XL, and c-MYC. The iPSC line expressed pluripotency markers, had a normal karyotype and trilineage differentiation potential.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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