Acta Crystallographica Section E (Sep 2011)

N-Cyclopropyl-N-[2-(2,4-difluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl]-2-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)acetamide dichloromethane 0.62-solvate

  • Nan Wang,
  • Huan-Mei Guo,
  • Gui-Ge Hou,
  • Xin-Yue Hu,
  • Qing-Guo Meng

DOI
https://doi.org/10.1107/S1600536811034295
Journal volume & issue
Vol. 67, no. 9
pp. o2464 – o2464

Abstract

Read online

In the title compound, C21H22F2N6O4·0.62CH2Cl2, the difluoro-substituted benzene ring forms dihedral angles of 54.6 (3)° with the mean plane of the thymine ring and 50.9 (2)° with the triazole ring. The dihedral angle between the thymine and triazole rings is 7.4 (3)°. In the crystal, intermolecular N—H...N and O—H...O hydrogen bonds link the main molecules into chains along [10overline{1}]. The CH2Cl2 solvent molecule was refined as partial occupancy over two sets of sites with refined occupancies of 0.308 (9) and 0.310 (8).