Clinical Case Reports (Jun 2024)

Gastrointestinal amyloidosis in a 50‐year‐old patient with miliary tuberculosis: A case report

  • Sameer Abdul Rauf,
  • Hussain Haider Shah,
  • Rahul Khatri,
  • Mansoor Ul Haq,
  • Tirth Dave,
  • Javaria Parwez Ali,
  • Syed Khizar Ali

DOI
https://doi.org/10.1002/ccr3.8978
Journal volume & issue
Vol. 12, no. 6
pp. n/a – n/a

Abstract

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Key Clinical Message This case highlights the importance of considering tuberculosis as an underlying cause of gastrointestinal amyloidosis, even in patients previously treated for the infection. Clinicians should maintain a high index of suspicion for atypical presentations of amyloidosis, especially in individuals with chronic inflammation, enabling early diagnosis and tailored management for improved patient outcomes. Abstract Gastrointestinal amyloidosis is a rare condition often associated with chronic inflammation. We present a unique case of a 50‐year‐old female with a history of miliary tuberculosis who developed gastrointestinal amyloidosis. The patient exhibited chronic loose stools, weight loss, abdominal pain, and urinary incontinence symptoms. Diagnostic workup revealed characteristic findings of amyloidosis on biopsy. Despite treatment for tuberculosis, her symptoms persisted, highlighting the challenging nature of managing this condition. This case underscores the importance of considering tuberculosis as a potential cause of secondary amyloidosis in patients with ongoing symptoms of inflammation and infection. Early recognition and tailored management are crucial in optimizing patient outcomes.

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