Toxicity testing of the veterinary use drugs

Abstract

Before the authorization for comercialization both medical and phyto-sanitary products must be tested for inocuity and toxicity, the risk assesment for persons working in drug industry, pharmacy, human beings and animals treated with the product and for the consummers of food products with drug residues being studied. The experimental studies of toxicity, after Milhaud et al., (1994), are classified in 7 groups: acute toxicity study; study of local irritant and allergic potential; study of mutagenic effect; subacute toxicity study; chronic toxicity and carcinogenic potential; study of embriotoxicity and adverse effect on reproduction; study of ecotoxicity.

Keywords

• toxicity testing
• veterinary drugs