Crystal structures of 3-methoxy-4-{[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]methoxy}benzonitrile and N-(4-{[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)acetamide

Abstract

The title compounds, C18H15N3O4 and C17H14ClN3O3, are heterocyclic 1,3,4-oxadiazole derivatives which differ from each other in the groups attached to the carbon atoms: a methoxyphenyl ring and a benzonitrile group in (I) and a chlorophenyl ring and an acetamide group in (II). Short intramolecular C—H...O hydrogen bonds occur in both molecules. The crystal structure of (I) features C—H...N hydrogen bonds, while in the crystal structure of (II), N—H...N, C—H...N and C—H...O hydrogen bonds are observed.

Keywords

• crystal structure
• oxadiazole derivatives
• superposition
• intramolecular C—H...O interactions
• intermolecular C—H...N and N—H...N hydrogen bonds