Antimicrobial resistance of Yersinia enterocolitica and presence of plasmid pYV virulence genes in human and animal isolates

T. Gkouletsos; K. Patas; G. Lambrinidis; H. Neubauer; L.D. Sprague; A. Ioannidis; S. Chatzipanagiotou

New Microbes and New Infections (Nov 2019)

Antimicrobial resistance of Yersinia enterocolitica and presence of plasmid pYV virulence genes in human and animal isolates

T. Gkouletsos,
K. Patas,
G. Lambrinidis,
H. Neubauer,
L.D. Sprague,
A. Ioannidis,
S. Chatzipanagiotou

Affiliations

T. Gkouletsos: Department of Biopathology and Clinical Microbiology, Aeginition Hospital, Medical School, National and Kapodistrian University of Athens, Greece; Department of Biological Applications and Technologies, University of Ioannina, Ioannina, Greece
K. Patas: Department of Biopathology and Clinical Microbiology, Aeginition Hospital, Medical School, National and Kapodistrian University of Athens, Greece
G. Lambrinidis: Division of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, Greece
H. Neubauer: Friedrich-Loeffler-Institut, Federal Research Institut for Animal Health, Institute for Bacterial Infections and Zoonoses, Jena, Germany
L.D. Sprague: Friedrich-Loeffler-Institut, Federal Research Institut for Animal Health, Institute for Bacterial Infections and Zoonoses, Jena, Germany
A. Ioannidis: Department of Biopathology and Clinical Microbiology, Aeginition Hospital, Medical School, National and Kapodistrian University of Athens, Greece; Department of Nursing, Faculty of Human Movement and Quality of Life Sciences, University of Peloponnese, Sparta, Greece
S. Chatzipanagiotou: Department of Biopathology and Clinical Microbiology, Aeginition Hospital, Medical School, National and Kapodistrian University of Athens, Greece; Corresponding author: S. Chatzipanagiotou, Department of Biopathology and Clinical Microbiology Athens Medical School, Aeginition Hospital, Vass. Sophias av. 72, 115 28 Athens, Greece.

Journal volume & issue: Vol. 32

Abstract

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Interactions between bacterial virulence and antimicrobial resistance are of increasing interest in clinical microbiology. On this account, antimicrobial resistance of Yersinia enterocolitica O:3 strains isolated from humans (n = 55), food-chain animals (n = 58) and companion animals (n = 13) was determined in relation to the absence or presence of the pYV plasmid-encoded virulence genes yadA and virF. There were no statistically significant associations between the rate of antimicrobial resistance and the presence or absence of the plasmid, in either human-derived or animal-derived strains. Therefore, it can be concluded that response to conventionally used antimicrobials in Y. enterocolitica O:3 strains is not dependent on pYV-encoded virulence determinants. Keywords: Antimicrobial resistance, pYV plasmid, virF, yadA, Yersinia enterocolitica

Published in New Microbes and New Infections

ISSN: 2052-2975 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: https://www.sciencedirect.com/journal/new-microbes-and-new-infections

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