767 Pre-clinical and first-in-human studies of HCW9218, a bifunctional TGF-β antagonist/IL-15 protein complex, in advanced solid tumors

• Peter R Rhode,
• Hing C Wong,
• Jack O Egan,
• Jeffrey S Miller,
• Manish Patel,
• Martin Felices,
• Philip M Arlen,
• Melissa A Geller,
• Pallavi Chaturvedi,
• Shannon Lunn,
• Bethany Hanke,
• Rose Wangen,
• Niraj Shrestha,
• Danieska Sandino,
• Karen L Kage,
• Delsy G Gaetano,
• Giles M Leclerc,
• Zhu Xiaoyun,
• Kelsey Mullen,
• Deepa Kolaseri Krishnadas

Affiliations

Peter R Rhode

Aff1 grid.422370.0Altor BioScience Corp. Miramar FL USA

Hing C Wong

Aff2 grid.422370.0Altor BioScience Corporation Miramar FL USA

Jack O Egan

Aff1 grid.422370.0Altor BioScience Corp. Miramar FL USA

Jeffrey S Miller

University of Minnesota, Minneapolis, MN, USA

Manish Patel

2University of Minnesota Medical Center, Minneapolis, MN, USA

Martin Felices

University of Minnesota, Minneapolis, MN, USA

Philip M Arlen

Genitourinary Malignancies, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA

Melissa A Geller

13 Department of Obstetrics, Gynecology & Women’s Health, Division of Gynecologic Oncology, University of Minnesota, Minneapolis, Minnesota, USA

Pallavi Chaturvedi

2HCW Biologics, Miramar, FL, USA

Shannon Lunn

1University of Minnesota, St. Paul, MN, USA

Bethany Hanke

1University of Minnesota, St. Paul, MN, USA

Rose Wangen

1University of Minnesota, St. Paul, MN, USA

Niraj Shrestha

2HCW Biologics, Miramar, FL, USA

Danieska Sandino

3HCW Biologics Inc., Miramar, FL, USA

Karen L Kage

3HCW Biologics Inc., Miramar, FL, USA

Delsy G Gaetano

3HCW Biologics Inc., Miramar, FL, USA

Giles M Leclerc

3HCW Biologics Inc., Miramar, FL, USA

Zhu Xiaoyun

3HCW Biologics Inc., Miramar, FL, USA

Kelsey Mullen

4University of Minnesota, Minneapolis, MN, USA

Deepa Kolaseri Krishnadas

4University of Minnesota, Minneapolis, MN, USA