Cranial aspergillosis in a patient receiving ibrutinib for chronic lymphocytic leukemia

Abstract

Cerebral abscess due to Aspergillus species is a relatively uncommon presentation, even amongst immunocompromised patients. However it is increasingly being recognized as a complication of ibrutinib therapy in patients with chronic lymphocytic leukemia. We present a case of cerebral abscesses caused by Aspergillus felis in a patient receiving ibrutinib for chronic lymphocytic leukemia. Keywords: Aspergillosis, Ibrutinib, Cerebral abscess, Chronic lymphocytic leukemia