Wild-Type Transthyretin Cardiac Amyloidosis in a Transplanted Heart

Lily K. Stern, MD; Pamela A. Ivey, MD; Corey J. Lum, DO; Shayaan Zaidi; Daniel Luthringer, MD; Angela Velleca, BSN, CCTC; Jon A. Kobashigawa, MD; Jignesh K. Patel, MD, PhD; Michelle M. Kittleson, MD, PhD

JACC: Case Reports (Aug 2023)

Wild-Type Transthyretin Cardiac Amyloidosis in a Transplanted Heart

Lily K. Stern, MD,
Pamela A. Ivey, MD,
Corey J. Lum, DO,
Shayaan Zaidi,
Daniel Luthringer, MD,
Angela Velleca, BSN, CCTC,
Jon A. Kobashigawa, MD,
Jignesh K. Patel, MD, PhD,
Michelle M. Kittleson, MD, PhD

Affiliations

Lily K. Stern, MD: Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA; Address for correspondence: Dr. Lily K. Stern, Smidt Heart Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Boulevard, AHSP Room A3120, Los Angeles, California 90048, USA.
Pamela A. Ivey, MD: Department of Cardiology, Intermountain Healthcare, Las Vegas, Nevada, USA
Corey J. Lum, DO: Department of Cardiology, Intermountain Healthcare, Las Vegas, Nevada, USA
Shayaan Zaidi: Department of Cardiology, Intermountain Healthcare, Las Vegas, Nevada, USA
Daniel Luthringer, MD: Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California, USA
Angela Velleca, BSN, CCTC: Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
Jon A. Kobashigawa, MD: Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
Jignesh K. Patel, MD, PhD: Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
Michelle M. Kittleson, MD, PhD: Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA

Journal volume & issue: Vol. 19
p. 101935

Abstract

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Wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM) is more prevalent than appreciated in the elderly. We present the case of an 88-year-old woman who underwent heart transplantation for ischemic cardiomyopathy and then presented 21 years later with new onset atrial flutter, found on endomyocardial biopsy to have new ATTRwt-CM. (Level of Difficulty: Advanced.)

Published in JACC: Case Reports

ISSN: 2666-0849 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.journals.elsevier.com/jacc-case-reports

About the journal

Abstract

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