RUDN Journal of Medicine (Dec 2011)
Early pregnancy and pandemic flu А(Н1N1)09
Abstract
We studied the course of pregnancy at 159 patients with flu A(H1N1)09 on early pregnancy terms. Control group consisted of 100 pregnants without flu which were in I-st trimester of gestation in the center of a pandemic flu during the same time. Reproductive losses in I trimester of pregnancy complicated by flu A(H1N1)09 were 32,1% (in a control group – 0%). Fetus malformations and spontaneous abortions are more often arose at a flu on 5–8 th weeks of gestation. There is a dependence between the mother's fever and early losses of pregnancy. There is not interrelation between a hyperthermia at the pregnant and fetus malformations. Oligohydramnion, II-nd stage of fetal hypotrophy and preterm labor are more often developed subsequently at patients with a flu A(H1N1)09 in I trimester of pregnancy. Preventive maintenance and flu treatment by an antiviral drags of Arbidolum in early terms of pregnancy reduces frequency of spontaneous abortions and doesn't render teratogenic influence.