Clinical Case Reports (Dec 2022)
COVID‐associated non‐vasculitic thrombotic retiform purpura of the face and extremities: A case report
- Connor M. Bunch,
- Nuha Zackariya,
- Anthony V. Thomas,
- Jack H. Langford,
- Michael Aboukhaled,
- Samuel J. Thomas,
- Aida Ansari,
- Shivani S. Patel,
- Hallie Buckner,
- Joseph B. Miller,
- Christy L. Annis,
- Margaret A. Quate‐Operacz,
- Leslie A. Schmitz,
- Joseph J. Pulvirenti,
- Jonathan C. Konopinski,
- Kathleen M. Kelley,
- Samer Hassna,
- Luke G. Nelligan,
- Mark M. Walsh
Affiliations
- Connor M. Bunch
- Departments of Emergency Medicine and Internal Medicine Henry Ford Hospital Detroit Michigan USA
- Nuha Zackariya
- Indiana University School of Medicine—South Bend South Bend Indiana USA
- Anthony V. Thomas
- Indiana University School of Medicine—South Bend South Bend Indiana USA
- Jack H. Langford
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Michael Aboukhaled
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Samuel J. Thomas
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Aida Ansari
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Shivani S. Patel
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Hallie Buckner
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Joseph B. Miller
- Departments of Emergency Medicine and Internal Medicine Henry Ford Hospital Detroit Michigan USA
- Christy L. Annis
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Margaret A. Quate‐Operacz
- Kidney Care of Michiana Mishawaka Indiana USA
- Leslie A. Schmitz
- Kidney Care of Michiana Mishawaka Indiana USA
- Joseph J. Pulvirenti
- Department of Infectious Disease Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Jonathan C. Konopinski
- Department of Pathology South Bend Medical Foundation South Bend Indiana USA
- Kathleen M. Kelley
- Department of Dermatology Beacon Medical Group Granger Indiana USA
- Samer Hassna
- Department of Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- Luke G. Nelligan
- Department of Family Medicine Marian University College of Osteopathic Medicine Indianapolis Indiana USA
- Mark M. Walsh
- Departments of Emergency Medicine and Internal Medicine Saint Joseph Regional Medical Center Mishawaka Indiana USA
- DOI
- https://doi.org/10.1002/ccr3.6790
- Journal volume & issue
-
Vol. 10,
no. 12
pp. n/a – n/a
Abstract
Abstract SARS‐CoV‐2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID‐19 illness. Aggressive anti‐COVID‐19 therapy with a high‐dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.
Keywords
