Frontiers in Medicine (Apr 2021)
Characteristics of Fundal Changes in Fundus Tessellation in Young Adults
- Hanyi Lyu,
- Hanyi Lyu,
- Hanyi Lyu,
- Hanyi Lyu,
- Hanyi Lyu,
- Qiuying Chen,
- Qiuying Chen,
- Qiuying Chen,
- Qiuying Chen,
- Guangyi Hu,
- Guangyi Hu,
- Guangyi Hu,
- Guangyi Hu,
- Ya Shi,
- Ya Shi,
- Ya Shi,
- Ya Shi,
- Luyao Ye,
- Luyao Ye,
- Luyao Ye,
- Luyao Ye,
- Yao Yin,
- Yao Yin,
- Yao Yin,
- Yao Yin,
- Ying Fan,
- Ying Fan,
- Ying Fan,
- Ying Fan,
- Haidong Zou,
- Haidong Zou,
- Haidong Zou,
- Haidong Zou,
- Jiangnan He,
- Jiangnan He,
- Jiangnan He,
- Jiangnan He,
- Jianfeng Zhu,
- Jianfeng Zhu,
- Jianfeng Zhu,
- Jianfeng Zhu,
- Xun Xu,
- Xun Xu,
- Xun Xu,
- Xun Xu
Affiliations
- Hanyi Lyu
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Hanyi Lyu
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Hanyi Lyu
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Hanyi Lyu
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Hanyi Lyu
- Ophthalmology Department of Peking University People's Hospital, Beijing, China
- Qiuying Chen
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Qiuying Chen
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Qiuying Chen
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Qiuying Chen
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Guangyi Hu
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Guangyi Hu
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Guangyi Hu
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Guangyi Hu
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Ya Shi
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Ya Shi
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Ya Shi
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Ya Shi
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Luyao Ye
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Luyao Ye
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Luyao Ye
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Luyao Ye
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Yao Yin
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Yao Yin
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Yao Yin
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Yao Yin
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Ying Fan
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Ying Fan
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Ying Fan
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Ying Fan
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Haidong Zou
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Haidong Zou
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Haidong Zou
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Haidong Zou
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jiangnan He
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Jiangnan He
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jiangnan He
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jiangnan He
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jianfeng Zhu
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Jianfeng Zhu
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jianfeng Zhu
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Jianfeng Zhu
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Xun Xu
- Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China
- Xun Xu
- Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
- Xun Xu
- Shanghai Jiaotong University School of Medicine, Shanghai, China
- Xun Xu
- Shanghai Engineering Center for Visual Science and Photo medicine, Shanghai Jiaotong University School of Medicine, Shanghai, China
- DOI
- https://doi.org/10.3389/fmed.2021.616249
- Journal volume & issue
-
Vol. 8
Abstract
Purpose: To explore the characteristics and associated factors of fundus tessellation, especially the alternation of choroidal thickness among different degrees of tessellated fundus in young adults.Design: Cross-sectional, population-based study.Methods: A total of 796 students were included in the study and underwent comprehensive ophthalmic examinations, including anterior segment examinations and swept-source optical coherence tomography (OCT) measurements. The degree of tessellated fundus was assessed by fundus photographs applying an early treatment of diabetic retinopathy study grid to evaluate the location of fundus tessellation and then divided into five groups. The topographic variation and factors, tilted disc ratio, parapapillary atrophy (PPA), retinal thickness (ReT), choroidal thickness (ChT), and subfoveal scleral thickness (SST) related to tessellated fundus were analyzed.Results: Compared to normal fundus, tessellated fundus had a lower spherical equivalent (SE) (p < 0.0001), worse best-corrected visual acuity (BCVA)(p = 0.043), longer axial length (AL) (p < 0.0001), thinner retina (p < 0.0001), thinner (p < 0.0001) choroid, and thinner sclera in center fovea (p = 0.0035). Among all subfields of macular and peripapillary regions, center fovea and macula-papillary region showed the most significant decrease in choroidal thickness. The proportion of fundus tessellation significantly increased with lower body weight index (BMI) (p = 0.0067), longer AL (p < 0.0001), larger PPA(p = 0.0058), thinner choroid (p < 0.0001), and thinner sclera (p < 0.0001).Conclusions: Eyes showed more severe myopic morphological alternation with the increasement of proportion of fundus tessellation to the center fovea, including a significant decrease in both choroid and scleral thickness. Choroidal thinning may progress most rapidly in the macula-papillary region as fundus tessellation approaches to the center fovea.
Keywords