Инновационная медицина Кубани (Jun 2022)

Application of cells of cord blood and umbilical cord: achievements, challenges and perspectives

  • I. V. Gilevich,
  • I. S. Polyakov,
  • V. A. Porhanov,
  • A. P. Storozhuk,
  • A. G. Zavgorodnyaya,
  • E. A. Kolomiytseva,
  • A. S. Sotnichenko

DOI
https://doi.org/10.35401/2541-9897-2022-25-2-67-76
Journal volume & issue
Vol. 0, no. 2
pp. 67 – 76

Abstract

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This review focuses on the biological aspects of the use of cord blood as a valuable source of cells. The distinctive features of hematopoietic stem cells, cells of the immune system, mesenchymal stem cells are described. The analysis of the results of clinical research and development of therapeutic approaches using cord blood cells and umbilical cord for the treatment of various diseases has been carried out.Currently, the target area of cord blood research is hematopoietic stem cell transplantation, as well as cellular immunotherapy of tumor diseases, treatment of neurological diseases and regenerative medicine.

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