Nature Communications (Jan 2021)

Bis-silylation of internal alkynes enabled by Ni(0) catalysis

  • Yun Zhang,
  • Xi-Chao Wang,
  • Cheng-Wei Ju,
  • Dongbing Zhao

DOI
https://doi.org/10.1038/s41467-020-20392-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

Read online

Bis-silylated alkenes offer the advantage of two functional handles with distinguished reactivity for downstream functionalization. Here, the authors report a nickel-catalyzed bis-silylation of internal alkynes to versatile silylated alkene intermediates which can be chemoselectively manipulated.