Dilated Cardiomyopathy in Pregnancy: A Review of ACEI Exposure and Fetal Risks

Abstract

Dilated cardiomyopathy (DCM) is a rare disease that can lead to serious cardiac complications, especially during pregnancy. In this study, a case of DCM in an advanced pregnancy with no known history of the disease resulting in spontaneous delivery is presented. Pregnancy in patients with DCM may have adverse outcomes because of increased cardiac output and plasma volume. This case demonstrates that pregnancy carries serious risks, particularly in patients with an ejection fraction <40%. The fetotoxic effects of angiotensin-converting enzyme inhibitors use during pregnancy are emphasized, and the importance of a multidisciplinary approach is highlighted.

Keywords

• dilated cardiomyopathy
• pregnancy
• angiotensin receptor blocker
• premature birth
• down syndrome