Jornal Vascular Brasileiro (Nov 2020)

Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2

  • Marcos Antonio Bonacorso Manhanelli Filho,
  • Eliud Garcia Duarte Júnior,
  • Jamil Victor de Oliveira Mariuba,
  • Fábio Linardi,
  • José Augusto Costa,
  • Julio Cesar Gali,
  • Winston Bonetti Yoshida,
  • Julio Cesar Gali Filho

DOI
https://doi.org/10.1590/1677-5449.200072
Journal volume & issue
Vol. 19

Abstract

Read online Read online

Abstract The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which turned out to be a SARS-CoV2 infection, and ended up developing arterial thrombosis with limb ischemia in a private care hospital in Sorocaba, São Paulo, Brazil. Considering this progression, we decided to intervene with low molecular weight heparin and Alprostadil, achieving a good clinical outcome. Our description aims to identify key points and clinical signs that offer evidence of the therapeutic window and a treatment option for coagulatory presentations of COVID-19.

Keywords