Identification of Metabolically Quiescent
<i>Leishmania mexicana</i>
Parasites in Peripheral and Cured Dermal Granulomas Using Stable Isotope Tracing Imaging Mass Spectrometry

mBio (Apr 2021)

Affiliations

Joachim Kloehn: Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science, University of Melbourne, Parkville, Victoria, Australia
Berin A. Boughton: Metabolomics Australia, University of Melbourne, Parkville, Victoria, Australia
Eleanor C. Saunders: Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science, University of Melbourne, Parkville, Victoria, Australia
Sean O’Callaghan: Metabolomics Australia, University of Melbourne, Parkville, Victoria, Australia
Katrina J. Binger: Department of Biochemistry and Genetics, La Trobe Institute for Molecular Sciences, La Trobe University, Bundoora, Victoria, Australia
Malcolm J. McConville: ORCiD; Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Science, University of Melbourne, Parkville, Victoria, Australia

Abstract

Many microbial pathogens switch between different growth and physiological states in vivo