Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes

Ji Qi; Chao Chen; Xiaoyan Zhang; Xianglong Hu; Shenglu Ji; Ryan T. K. Kwok; Jacky W. Y. Lam; Dan Ding; Ben Zhong Tang

doi:10.1038/s41467-018-04222-8

Nature Communications (May 2018)

Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes

Ji Qi,
Chao Chen,
Xiaoyan Zhang,
Xianglong Hu,
Shenglu Ji,
Ryan T. K. Kwok,
Jacky W. Y. Lam,
Dan Ding,
Ben Zhong Tang

Affiliations

Ji Qi: Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Institute for Advanced Study, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay
Chao Chen: State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
Xiaoyan Zhang: State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
Xianglong Hu: Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Institute for Advanced Study, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay
Shenglu Ji: State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
Ryan T. K. Kwok: Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Institute for Advanced Study, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay
Jacky W. Y. Lam: Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Institute for Advanced Study, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay
Dan Ding: State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
Ben Zhong Tang: Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Institute for Advanced Study, Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay

DOI: https://doi.org/10.1038/s41467-018-04222-8
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 12

Abstract

Read online

The combination of imaging techniques in cancer treatment often involves a trade-off in properties due to the opposite working mechanisms. Here, the authors report on a material that avoids the trade-off by switching from photoacoustic imaging to fluorescence imaging upon an external light trigger

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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