Aggressive prolactinomas responsive to temozolomide treatment: Report of two cases

Abstract

Abstract Refractory aggressive prolactinomas are detected after the unresponsiveness to conventional therapies. We report two cases that underwent temozolomide treatment and have been in near‐complete remission ever since. We suggest the pathology techniques for earlier detection and, subsequently, treatment with temozolomide to reduce morbidities and better respond to therapy.

Keywords

• aggressive prolactinoma
• case report
• pituitary neoplasms
• prolactinoma
• temozolomide