PREVALENCES OF COAGULOPATHES IN DIFFERENT PROVINCES OF IRAN

Abstract

Prevalence of coagulopathies (n=6010) including factor VIII deficient (haemophilia A) individuals (n=3205) were investigated and analysed in 24 provinces of Iran. For all coagulopathies, the prevalence (per 100,000) was the highest with 24.45 in Semnan (north east of Iran), followed by Hamadan (west) with 17.56, the lowest was observed in Kordestan (west) as 0.88, followed by Kohkiluyeh & Boyr-Ahmad (centre) and Esfahan (centre) as 1.20 and 1.32, respectively. For haemophilia A, the highest was observed also in Semnan as 14.19, followed by Hamadan as 9.81. The lowest was observed in Hormozgan (south east) as 0.17, followed by Kohkiluyeh & Boyr-Ahmad as 0.20. The analyses showed that a higher prevalence exited above a hypothetical geographical centre line, from west to east of Iran; a lower prevalence was observed below the line.

Keywords

• Coagulopathies
• Haemophilia A
• Genetic epidemiology