Nature Communications (Feb 2017)
A genome-wide association study yields five novel thyroid cancer risk loci
- Julius Gudmundsson,
- Gudmar Thorleifsson,
- Jon K. Sigurdsson,
- Lilja Stefansdottir,
- Jon G. Jonasson,
- Sigurjon A. Gudjonsson,
- Daniel F. Gudbjartsson,
- Gisli Masson,
- Hrefna Johannsdottir,
- Gisli H. Halldorsson,
- Simon N. Stacey,
- Hannes Helgason,
- Patrick Sulem,
- Leigha Senter,
- Huiling He,
- Sandya Liyanarachchi,
- Matthew D. Ringel,
- Esperanza Aguillo,
- Angeles Panadero,
- Enrique Prats,
- Almudena Garcia-Castaño,
- Ana De Juan,
- Fernando Rivera,
- Li Xu,
- Lambertus A. Kiemeney,
- Gudmundur I. Eyjolfsson,
- Olof Sigurdardottir,
- Isleifur Olafsson,
- Hoskuldur Kristvinsson,
- Romana T. Netea-Maier,
- Thorvaldur Jonsson,
- Jose I. Mayordomo,
- Theo S. Plantinga,
- Hannes Hjartarson,
- Jon Hrafnkelsson,
- Erich M. Sturgis,
- Unnur Thorsteinsdottir,
- Thorunn Rafnar,
- Albert de la Chapelle,
- Kari Stefansson
Affiliations
- Julius Gudmundsson
- deCODE genetics/AMGEN
- Gudmar Thorleifsson
- deCODE genetics/AMGEN
- Jon K. Sigurdsson
- deCODE genetics/AMGEN
- Lilja Stefansdottir
- deCODE genetics/AMGEN
- Jon G. Jonasson
- Landspitali-University Hospital
- Sigurjon A. Gudjonsson
- deCODE genetics/AMGEN
- Daniel F. Gudbjartsson
- deCODE genetics/AMGEN
- Gisli Masson
- deCODE genetics/AMGEN
- Hrefna Johannsdottir
- deCODE genetics/AMGEN
- Gisli H. Halldorsson
- deCODE genetics/AMGEN
- Simon N. Stacey
- deCODE genetics/AMGEN
- Hannes Helgason
- deCODE genetics/AMGEN
- Patrick Sulem
- deCODE genetics/AMGEN
- Leigha Senter
- Division of Human Genetics, Ohio State University Comprehensive Cancer Center
- Huiling He
- Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center
- Sandya Liyanarachchi
- Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center
- Matthew D. Ringel
- Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University
- Esperanza Aguillo
- Division of Endocrinology, University Hospital
- Angeles Panadero
- Division of Medical Oncology, Ciudad de Coria Hospital
- Enrique Prats
- Division of Nuclear Medicine, University Hospital
- Almudena Garcia-Castaño
- Division of Medical Oncology, Marques de Valdecilla University Hospital
- Ana De Juan
- Division of Medical Oncology, Marques de Valdecilla University Hospital
- Fernando Rivera
- Division of Medical Oncology, Marques de Valdecilla University Hospital
- Li Xu
- Department of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center
- Lambertus A. Kiemeney
- Radboud University Medical Centre, Radboud Institute for Health Sciences
- Gudmundur I. Eyjolfsson
- The Laboratory in Mjodd
- Olof Sigurdardottir
- Department of Clinical Biochemistry, Akureyri Hospital
- Isleifur Olafsson
- Landspitali-University Hospital
- Hoskuldur Kristvinsson
- Landspitali-University Hospital
- Romana T. Netea-Maier
- Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Radboud Institute for Health Sciences
- Thorvaldur Jonsson
- Landspitali-University Hospital
- Jose I. Mayordomo
- University of Colorado Hospital
- Theo S. Plantinga
- Department of Pathology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences
- Hannes Hjartarson
- Landspitali-University Hospital
- Jon Hrafnkelsson
- Landspitali-University Hospital
- Erich M. Sturgis
- Department of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center
- Unnur Thorsteinsdottir
- deCODE genetics/AMGEN
- Thorunn Rafnar
- deCODE genetics/AMGEN
- Albert de la Chapelle
- Department of Cancer Biology and Genetics, Ohio State University Comprehensive Cancer Center
- Kari Stefansson
- deCODE genetics/AMGEN
- DOI
- https://doi.org/10.1038/ncomms14517
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 8
Abstract
Non-medullary thyroid cancers include papillary and follicular subtypes, and are the most common type of thyroid cancer. Here, the authors extend previous work by performing a large genome-wide association study and find five novel loci associated with this disease.
